| Date | Event |
|---|---|
| 1539 | Pierre Clereau Was Born |
| 1539 | Fabrizio Dentice Was Born |
| 1539 | Paschal de l'Estocart Was Born |
| 1539 | Johannes Lupi Died |
| 1539 | Ambrose Lupo Was Born |
| January 14 1539 | Spain Annexes Cuba |
| April 19 1539 | Charles V, Protestants Sign Frankfurt Treaty |
| April 27 1539 | Federmann, De Belalcazar Re-found Bogota |
| May 30 1539 | Hernando De Soto Lands At Tampa Bay |
| June 03 1539 | Hernando De Soto Claims Florida For Spain |
| June 10 1539 | Pope Paul III Delays Council Due To Difficulties |
| October 06 1539 | De Soto Enters Anhaica By Force |