| Date | Event |
|---|---|
| 1541 | Vincenzo Bellavere Was Born |
| 1541 | Hernando de Cabezón Was Born |
| 1541 | Lupus Hellinck Died |
| 1541 | Hans Kotter Died |
| 1541 | Francesco Rovigo Was Born |
| January 15 1541 | French King Francis Approves New France Colonization |
| February 12 1541 | Pedro De Valdivia Founded Santiago, Chile |
| April 07 1541 | Xavier Leaves Lisbon On Portuguese Mission |
| May 08 1541 | De Soto Reaches Mississippi River |
| June 26 1541 | Francisco Pizarro Assassinated In Lima |
| August 23 1541 | Cartier Completes 3rd Canada Voyage |
| August 29 1541 | The Ottoman Turks Capture The Hungarian Capital, Buda |
| September 11 1541 | Michimalonco Destroyed Santiago, Chile |
| September 13 1541 | John Calvin Returns To Geneva To Reform Church |
| September 30 1541 | Spanish Conquistadors Encounter Tula Resistance |
| December 10 1541 | Culpepper, Dereham Executed: Affairs With Queen Catherine |