| Date | Event |
|---|---|
| 1581 | Antoine de Bertrand Died |
| 1581 | Rodrigo de Ceballos Died |
| 1581 | Joachim Thibault de Courville Died |
| 1581 | Fabrizio Dentice Died |
| 1581 | Johann Staden Was Born |
| May 07 1581 | Alexander Utendal Died |
| January 16 1581 | The English Parliament Outlaws Roman Catholicism |
| April 04 1581 | Francis Drake Knighted |
| July 26 1581 | Northern Low Countries Declare Their Independence |