| Date | Event |
|---|---|
| 1621 | Giulio Belli Died |
| 1621 | Giovanni Battista Granata Was Born |
| 1621 | Matthew Locke Was Born |
| 1621 | Georg Neumark Was Born |
| 1621 | Michael Praetorius Died |
| 1621 | Francesco Rasi Died |
| 1621 | Giovanni Battista Riccio Died |
| 1621 | Heinrich Schwemmer Was Born |
| 1621 | Francesco Soriano Died |
| 1621 | Jan Pieterszoon Sweelinck Died |
| February 09 1621 | Gregory XV Elected Pope By Acclamation |
| February 17 1621 | Standish Is Appointed As Commander Of Colony |
| March 16 1621 | Samoset Visits Settlers Of Plymouth Colony |
| March 22 1621 | Plymoutn Pillgrims & Wampanoags Sign Treaty |
| April 05 1621 | Mayflower Returns To England From Massachusetts |
| May 24 1621 | The Protestant Union Is Formally Dissolved |
| June 03 1621 | Charter Received By Dutch West India Company |
| June 21 1621 | 27 Czech Noblemen Executed In Prague |